Infliximab (trade names Remicade, Inflectra, Remsima) is an anti-TNF (anti-tumour necrosis factor) drug. TNF is a protein which is found in everyone’s blood as part of the body’s normal response to infection. However, in rheumatoid arthritis and some other inflammatory diseases abnormal production of TNF causes inflammation and damage to bones, cartilage and tissue. Anti-TNF drugs block the action of TNF and so reduce this inflammation.